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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
15.15
Human Site:
S285
Identified Species:
25.64
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S285
Q
T
P
K
E
M
K
S
P
V
V
F
S
Q
E
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S285
Q
T
X
K
E
M
K
S
P
V
V
F
S
Q
E
Rhesus Macaque
Macaca mulatta
P56490
532
60122
C303
K
A
E
Q
L
T
T
C
S
S
Y
P
S
S
E
Dog
Lupus familis
XP_541769
536
61594
S334
Q
D
S
E
E
M
K
S
P
S
V
F
R
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S284
S
E
D
P
K
V
T
S
P
T
V
F
S
Q
E
Rat
Rattus norvegicus
P31390
486
55674
S284
S
E
D
P
K
M
T
S
P
T
V
F
S
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
D288
K
V
V
I
K
E
Q
D
G
D
V
V
V
K
E
Chicken
Gallus gallus
P30372
466
51547
C277
G
E
S
V
M
E
N
C
V
Q
G
E
E
K
D
Frog
Xenopus laevis
P30544
484
54107
T292
Q
T
A
E
E
K
E
T
S
N
E
S
S
S
A
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
R318
E
M
T
S
E
P
K
R
K
M
C
Y
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
E326
G
S
N
E
E
E
D
E
N
A
I
S
P
D
I
Honey Bee
Apis mellifera
XP_395477
546
60788
G340
S
T
E
K
Q
T
G
G
S
V
A
P
T
E
T
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
R297
F
H
A
R
E
S
T
R
L
L
L
K
Q
V
S
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
K393
E
K
E
A
L
A
I
K
Q
V
K
R
I
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
13.3
66.6
N.A.
46.6
53.3
N.A.
13.3
0
26.6
13.3
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
93.3
26.6
73.3
N.A.
60
60
N.A.
40
13.3
46.6
46.6
N.A.
26.6
40
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
8
0
8
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% C
% Asp:
0
8
15
0
0
0
8
8
0
8
0
0
0
8
8
% D
% Glu:
15
22
22
22
50
22
8
8
0
0
8
8
8
8
50
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% F
% Gly:
15
0
0
0
0
0
8
8
8
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
8
0
8
0
8
% I
% Lys:
15
8
0
22
22
8
29
8
8
0
8
8
8
22
8
% K
% Leu:
0
0
0
0
15
0
0
0
8
8
8
0
0
8
0
% L
% Met:
0
8
0
0
8
29
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
8
15
0
8
0
0
36
0
0
15
8
0
8
% P
% Gln:
29
0
0
8
8
0
8
0
8
8
0
0
8
36
0
% Q
% Arg:
0
0
0
8
0
0
0
15
0
0
0
8
8
0
0
% R
% Ser:
22
8
15
8
0
8
0
36
22
15
0
15
43
15
8
% S
% Thr:
0
29
8
0
0
15
29
8
0
15
0
0
8
0
8
% T
% Val:
0
8
8
8
0
8
0
0
8
29
43
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _